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Reproductive toxicity study with a novel deoxyguanosine analogue (Metacavir) in pregnant SD rats

Qihui Luo,Zhengli Chen,Anchun Cheng,Mingshu Wang,Jing Fang,Xi Peng,Li Tang

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 82-89 doi: 10.1007/s11684-015-0376-0

Abstract: In this study, the maternal toxicity, embryo-fetal developmental toxicity and teratogenicity were studiedof 200 mg/(kg·d) (i.e., 40 times the effective dose in rats), Metacavir shows some maternal toxicity

Keywords： deoxyguanosine analogue     Metacavir     pregnancy     maternal toxicity     embryo toxicity     teratogenicity    

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Free radical scavenging window of infertile patients with polycystic ovary syndrome: correlation with embryo

Bo Huang, Zhou Li, Xinling Ren, Jihui Ai, Lixia Zhu, Lei Jin

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 247-252 doi: 10.1007/s11684-017-0519-6

Abstract: follicular fluid was related to ovarian responsiveness, in vitro fertilization (IVF), and embryoHowever, studies analyzing the relationship between the free radical scavenging capacity and embryo qualityto evaluate the relationship between the free radical scavenging window of women with PCOS and their embryo

Keywords： in vitro fertilization     PCOS     free radical     embryo quality    

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Propensity score-matched study and meta-analysis of cumulative outcomes of day 2/3 versus day 5/6 embryo

Ye Yin, Ge Chen, Kezhen Li, Qiuyue Liao, Sijia Zhang, Nieying Ma, Jing Chen, Yan Zhang, Jihui Ai

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 563-569 doi: 10.1007/s11684-017-0535-6

Abstract:

The superiority of the cumulative outcomes of day 5/6 embryo transfer to those of day 2/3 embryo transfer1.70) and cumulative live birth rate (53.00% vs. 49.77%, OR 1.14, 95% CI 0.78–1.66) of day 5/6 embryotransfers were higher than those of day 2/3 embryo transfers, but this difference was not significantThis study demonstrated that day 5/6 embryo transfer is a more cost-effective and time-efficient policythan day 2/3 embryo transfer to produce a live baby.

Keywords： blastocyst     embryo transfer     cumulative pregnancy rate     cumulative live birth rate     IVF    

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Embryo-mediated genome editing for accelerated genetic improvement of livestock

Zachariah MCLEAN, Björn OBACK, Götz LAIBLE

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 2,   Pages 148-160 doi: 10.15302/J-FASE-2019305

Abstract: However, embryo-mediated precision editing by homology-directed repair (HDR) mechanisms is currentlyThis review provides a summary of genome editing in bovine embryos and proposes an embryo-mediated acceleratedIt integrates embryo-based genomic selection with precise multi-editing and uses embryonic cloning with

Keywords： animal breeding     cattle     cloning     CRISPR/Cas9     cytoplasmic injection     embryo     genome editing     germline chimaeras    

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Accelerating the Industrialization of Embryo Transfer Technology and Developing National Cattle Industry

Guo Zhiqin

Strategic Study of CAE 2000, Volume 2, Issue 3,   Pages 12-17

Abstract: Embryo transfer is the best way for cattle improvement ,for it has the following advantages: simple operationsresearch status, the key technology and the necessity and possibility of industrialization of China* s embryoMeasures and methods for the application of embryo transfer technology to dairy and beef cattle are proposed

Keywords： embryo transfer     industrialization     cattle industry    

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Interaction and combined toxicity of microplastics and per- and polyfluoroalkyl substances in aquatic

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 10, doi: 10.1007/s11783-022-1571-2

Abstract:

● Adsorption of PFASs on MPs and its mechanisms are critically reviewed.

Keywords： Microplastics     Per- and Polyfluoroalkyl substances     Adsorption     Transport     Transformation    

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Product identification and toxicity change during oxidation of methotrexate by ferrate and permanganate

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 7, doi: 10.1007/s11783-021-1501-8

Abstract:

• Oxidation of methotrexate by high-valent metal-oxo species was first explored.

Keywords： Anticancer drugs     High-valent metal-oxo species     Oxidation kinetics     Reaction mechanisms     Multi-endpoint toxicity    

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Evaluation of soil microbial toxicity of waste foundry sand for soil-related reuse

Haifeng ZHANG, Lu SU, Xiangyu LI, Jiane ZUO, Guangli LIU, Yujue WANG

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 1,   Pages 89-98 doi: 10.1007/s11783-013-0591-3

Abstract: The relationship between the chemical contaminants and soil microbial toxicity of waste foundry sandThe soil microbial toxicity of each WFS was evaluated by measuring the dehydrogenase activity (DHA) of, the WFSs with higher concentrations of metal and organic contaminants exhibited greater microbial toxicity

Keywords： waste foundry sand     toxicity     bioassay     soil microbial activity     waste reuse    

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ROUTE DEVELOPMENT, ANTIVIRAL STUDIES, FIELD EVALUATION AND TOXICITY OF AN ANTIVIRAL PLANT PROTECTANT

Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 1, doi: 10.15302/J-FASE- 2021390

Abstract: permitting further assessment of its antivirus activity in the greenhouse and field experiments, and toxicityThe toxicity tests showed that NK0238 was not acutely toxic to birds, fish, honey bees and silkworms.optimized route provides a solid foundation for its large-scale synthesis and subsequent efficacy and toxicity

Keywords： protectant / antiviral in the greenhouse / field evaluation / l-trp-NCA / synthesis optimization / toxicity    

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Understanding the role of nano-TiO on the toxicity of Pb on through modeling–Is it additive or synergistic

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 5, doi: 10.1007/s11783-021-1493-4

Abstract: ItemContent>

• A two-compartment model is able to quantify the effect of nano-TiO2 on Pb toxicity

Keywords： Algae     C. dubia     Lead     Nano-TiO2     Synergistic toxicity     Two-compartment toxicokinetic-toxicodynamic    

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Toxicity models of metal mixtures established on the basis of “additivity” and “interactions”

Yang Liu,Martina G. Vijver,Bo Pan,Willie J. G. M. Peijnenburg

Frontiers of Environmental Science & Engineering 2017, Volume 11, Issue 2, doi: 10.1007/s11783-017-0916-8

Abstract: · No preference is set between CA and IA models to assess toxicity of metal mixtures. · Increased modelThis review summarizes the existing predictive tools for evaluating the combined toxicity of metals presentbackground information on how to make good use of the tools and how to advance the methods for assessing toxicityTo improve the reliability of toxicity modeling for metal mixtures, further efforts should focus on balancingrelationship between the significance of statistics and the biological meaning, and unraveling the toxicity

Keywords： Metal     Mixtures     Toxicity     Additivity     Modeling     Interactions    

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Leaching toxicity characteristics of municipal solid waste incineration bottom ash

Khamphe PHOUNGTHONG,Yi XIA,Hua ZHANG,Liming SHAO,Pinjing HE

Frontiers of Environmental Science & Engineering 2016, Volume 10, Issue 2,   Pages 399-411 doi: 10.1007/s11783-015-0819-5

Abstract: and hierarchical cluster analysis, were used to evaluate the contributions of the constituents to the toxicity

Keywords： Municipal solid waste incineration     bottom ash     alternative material     leaching tests     toxicity     Vibrio    

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Toxicity-oriented water quality engineering

Shengkun Dong, Chenyue Yin, Xiaohong Chen

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 5, doi: 10.1007/s11783-020-1259-4

Abstract: • Toxicity-oriented water quality monitoring was proposed. • Toxicity-oriented water quality engineeringSpecifically, complementary to traditional water quality parameters, we evaluated the water toxicitysubsequently investigated the performance of some of the water treatment strategies in modulating the water toxicityMoreover, we implemented the toxicity concept into existing water treatment design theory to facilitatetoxicity-oriented water quality control designs.

Keywords： Water     Wastewater     Mixture     Toxicity     Monitor     Control    

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Assessment of toxicity of two nitroaromatic compounds in the freshwater fish

Hongyan SHEN, Jixi GAO, Jinsheng WANG

Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 4,   Pages 518-523 doi: 10.1007/s11783-012-0427-6

Abstract: A freshwater fish bioassay based on the 96 h was used to estimate the single and joint toxicity ofThe toxicity of -nitrotoluene was greater than that of -nitroaniline based on 96 h values of 40.74Both compounds had moderate toxicity toward , and this toxicity increased with the exposure durationor toxicity.Further research is needed to investigate the combined effects and sublethal toxicity of -nitrotoluene

Keywords： joint toxicity     Cyprinus carpio     LC50     p-nitrotoluene    

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Predictive models on photolysis and photoinduced toxicity of persistent organic chemicals

Qing ZHANG

Frontiers of Environmental Science & Engineering 2013, Volume 7, Issue 6,   Pages 803-814 doi: 10.1007/s11783-013-0547-7

Abstract: structure-activity relationship (QSAR) models that relate photodegradation kinetics or photoinduced toxicitymedia including liquid phase, gaseous phase, surfaces of plant leaves, and QSAR models on photoinduced toxicityFurther prospects for QSAR model development on photodegradation kinetics and photoinduced toxicity of

Keywords： quantitative structure-activity relationship (QSAR) models     photodegradation     persistent organic pollutants     environmental media     mechanisms    

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Title Author Date Type Operation

Reproductive toxicity study with a novel deoxyguanosine analogue (Metacavir) in pregnant SD rats

Qihui Luo,Zhengli Chen,Anchun Cheng,Mingshu Wang,Jing Fang,Xi Peng,Li Tang

Journal Article

Free radical scavenging window of infertile patients with polycystic ovary syndrome: correlation with embryo

Bo Huang, Zhou Li, Xinling Ren, Jihui Ai, Lixia Zhu, Lei Jin

Journal Article

Propensity score-matched study and meta-analysis of cumulative outcomes of day 2/3 versus day 5/6 embryo

Ye Yin, Ge Chen, Kezhen Li, Qiuyue Liao, Sijia Zhang, Nieying Ma, Jing Chen, Yan Zhang, Jihui Ai

Journal Article

Embryo-mediated genome editing for accelerated genetic improvement of livestock

Zachariah MCLEAN, Björn OBACK, Götz LAIBLE

Journal Article

Accelerating the Industrialization of Embryo Transfer Technology and Developing National Cattle Industry

Guo Zhiqin

Journal Article

Interaction and combined toxicity of microplastics and per- and polyfluoroalkyl substances in aquatic

Journal Article

Product identification and toxicity change during oxidation of methotrexate by ferrate and permanganate

Journal Article

Evaluation of soil microbial toxicity of waste foundry sand for soil-related reuse

Haifeng ZHANG, Lu SU, Xiangyu LI, Jiane ZUO, Guangli LIU, Yujue WANG

Journal Article

ROUTE DEVELOPMENT, ANTIVIRAL STUDIES, FIELD EVALUATION AND TOXICITY OF AN ANTIVIRAL PLANT PROTECTANT

Journal Article

Understanding the role of nano-TiO on the toxicity of Pb on through modeling–Is it additive or synergistic

Journal Article

Toxicity models of metal mixtures established on the basis of “additivity” and “interactions”

Yang Liu,Martina G. Vijver,Bo Pan,Willie J. G. M. Peijnenburg

Journal Article

Leaching toxicity characteristics of municipal solid waste incineration bottom ash

Khamphe PHOUNGTHONG,Yi XIA,Hua ZHANG,Liming SHAO,Pinjing HE

Journal Article

Toxicity-oriented water quality engineering

Shengkun Dong, Chenyue Yin, Xiaohong Chen

Journal Article

Assessment of toxicity of two nitroaromatic compounds in the freshwater fish

Hongyan SHEN, Jixi GAO, Jinsheng WANG

Journal Article

Predictive models on photolysis and photoinduced toxicity of persistent organic chemicals

Qing ZHANG

Journal Article